UMR_S 1064 Center for Research in Transplantation and Translational Immunology

Annuaire de la recherche en pneumologie 

Nom du LaboratoireUMR_S 1064 Center for Research in Transplantation and Translational Immunology
N° d’équipeUMR_S 1064 CR2Ti équipe 4
Nom du directeur du laboratoireJOSIEN Régis
Nom du responsableDr BROUARD Sophie
Courriel du responsablesophie.brouard@univ-nantes.fr
Contacts principauxDr David Lair PhD : david.lair@chu-nantes.fr
Dr Adrien Tissot MD-PhD : adrien.tissot@univ-nantes.fr
Dr Sophie Brouard DV-PhD : sophie.brouard@univ-nantes.fr
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AdresseCHU Nantes – Hôtel Dieu 30 Bd Jean Monnet
CP44093
VilleNantes Cedex 01
PaysFrance
Téléphone : +33 (0)2 40 08 74 10
Fax+33 (0)2 40 08 74 11
Site internethttps://cr2ti.univ-nantes.fr
Mots clésTransplantation pulmonaire- asthme- biomarqueurs-rejet chronique – médecine personnalisée
RésuméTeam 4 has a long-standing expertise and interest in the analysis of immune responses in transplantation and autoimmune diseases. The contribution of adaptive cellular and humoral subsets is analyzed in the pathogenic response leading to allograft rejection and autoimmune diseases but also in the achievement of immune tolerance. Our research is focused primarily on human thanks to the tight connection with clinical departments, the establishment of large biocollection of human samples (Kidney and Lung allo-transplantation; Auto-immune hepatitis, Anca-associated vasculitis) and the large scientific expertise of Team4 researchers (B cell, CD4 and CD8 T cells, endothelial cells). DORI-t aims to integrate the knowledge from basic research studies into translational research programs to develop innovative healthcare strategies in solid organ transplantation (kidney, lung, liver) and in autoimmune diseases.
Axe principalTransplantation-Asthme

Annuaire de la recherche en pneumologie 

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